A breakthrough engine for health. At global scale.

Wellcome Leap builds bold, unconventional programs, and funds them at scale. Programs optimized to deliver breakthroughs in human health over 5 – 10 years and demonstrate seemingly impossible results on seemingly impossible timelines.

Wellcome Leap is a global ARPA for health.

In 5 years, executing 13 programs in 30 countries.

$50M Program

the missed vital sign

What if we could reduce the time it takes to get effective treatment for heavy menstrual bleeding from 5 years to 5 months?

$50M Program

care

What if endocrinology could prevent Alzheimer's?

$50M Program

Untangling Addiction

What if we treated addiction like we treat cancer, as a curable, biological illness?

$60M Program

Dynamic Resilience

What if our health span matched our life span?

$50M Supported Challenge

Q4Bio

What if we could develop new algorithms that deliver quantum advantage for health?

$50M Program

SAVE

What if we could shorten and improve training and not all surgical providers needed to be MDs?

$50M Program

In Utero

What if we could reduce the number of stillborn babies by half by detecting emerging complications in utero?

R3 Global

What if a distributed network of biofoundries could produce mRNA biologics for cancer, Zika, or RA, and also surge capacity in the advent of a pandemic?

$50M Program

Multi-Channel Psych

What if we could double the number of people who receive an effective treatment for depression? On the first try.

$55M Program

Delta Tissue

What if we could predict future disease progression for an individual so as to target treatments today?

$45M Program

1kD

What if we've been approaching the first 3 years of a child's development all wrong?

$50M Program

HOPE

What if we could bioengineer a kidney that restores enough function to eliminate dialysis?

Researchers working together to solve problems they can’t solve alone.

A new worldwide network of scientists and engineers is demonstrating how philanthropy can leverage a 60-year proven innovation model to solve urgent global problems. Now over 170 organizations on 6 continents, representing more than 1,500,000 researchers.

The world’s largest research network, ready for instant activation.

Network shown at midpoint of first five programs.

Using a 60+ year proven model of innovation.

Wellcome Leap is built on a unique model of innovation practiced at DARPA.

For more than six decades, this model has been an uninterrupted engine of breakthrough innovation. It is not a discovery science model, but neither is it a pure application model.

It sits firmly at the intersection of the two.

A 2x2 research matrix categorizing 'Basic Research,' 'Use-Inspired Research,' 'Applied Research,' with arrows highlighting discovery science, breakthroughs, and inventing.

This kind of work is hard.
The hard is what makes it great.

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